Gender or Cross-cultural?

On my opinion, yes, the difference between males and females communicating is similar to the difference between people from two different cultures. For example, when a men and a woman are getting to know each other, there could be a lot of misunderstandings. It is the same when you go into a country with a different culture, even if they speak your native language. There will be a lot of misunderstanding at the beginning. However, after some time, you may think that you know how people from that particular culture may communicate. It is the same in a couple, you can get know each other and how to communicate. Of course, the difference will be there always, but you get to identify them.

And of course, there could be a mixed cultural marriage.